Symbol
Name
ID

Aqp2
aquaporin 2
MGI:1096865

Phenotype annotations related to renal/urinary system

Darker colors indicate more annotations

Human Phenotypes	Hyposthenuria	Megacystis	Functional abnormality of the bladder	Enuresis nocturna	Polyuria	Renal insufficiency	Hydroureter
Disease(s) Associated with AQP2	Hyposthenuria	Megacystis	Functional abnormality of the bladder	Enuresis nocturna	Polyuria	Renal insufficiency	Hydroureter
nephrogenic diabetes insipidus
nephrogenic diabetes insipidus type 2

Mouse Phenotypes

kidney medulla cyst

abnormal urine homeostasis

colorless urine

abnormal urine osmolality

decreased urine osmolality

abnormal kidney morphology

dilated kidney collecting duct

kidney collecting duct atrophy

renal interstitial fibrosis

abnormal kidney medulla morphology

abnormal kidney pyramid morphology

kidney papillary atrophy

kidney medulla atrophy

abnormal kidney pelvis morphology

dilated kidney calyx

hydronephrosis

dilated renal tubule

hydroureter

ureterovesical junction obstruction

abnormal urinary bladder morphology

abnormal kidney physiology

polyuria

Availability

Mouse Genotype

Aqp2^cph/Aqp2^cph

Aqp2^F204V/Aqp2^F204V

Aqp2^tm1(cre)Blyg/Aqp2^tm1(cre)Blyg

Aqp2^tm1.1Ask/Aqp2^tm1.1Ask

Aqp2^tm1.1Nlsn/Aqp2^tm1.1Nlsn

Aqp2^tm1Ask/Aqp2^tm1Ask

Aqp2^tm1Bxy/Aqp2^tm1Bxy
Tg(CAG-cre/Esr1*)5Amc/0 (conditional)

Aqp2^tm1Nlsn/Aqp2^tm1Nlsn
Tg(Hoxb7-cre)13Amc/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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